A 23-year-old male with an atypical presentation was diagnosed with a rare case of left-sided isolated testicular tuberculosis (TB). Testicular TB is an uncommon form of genitourinary TB, characterized by painful or painless swelling of the testicles, sometimes accompanied by scrotal ulceration or discharging sinus. The epididymis is often affected as well. Genital TB is frequently associated with TB involvement in the kidneys or lower urinary tract, leading to lower urinary tract symptoms in affected patients. High-resolution ultrasonography (HRUS) is the recommended method for assessment due to the lack of definitive signs distinguishing genitourinary TB from testicular malignancy. Once testicular TB is confirmed, the primary treatment approach is anti-TB chemo-therapy, aiming for complete resolution of the lesion. However, in rare cases, orchidectomy may
be necessary for both diagnostic and therapeutic purposes. In this case, the patient underwent a 6-month regimen of anti-TB chemotherapy, resulting in a complete cure of
the isolated testicular TB.
Keywods: Pulmonary tuberculosis, High-resolution ultrasonography, anti-TB chemotherapy, Extra-pulmonary TB